The Human Exposome

The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.

It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.

The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains one person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.

The Human Exposome

The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.

It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.

The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains onea person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.

The Human Exposome

Latest News

Highlights from the ATHLETE project's sixth annual consortium meeting

Highlights from the ATHLETE project’s sixth annual consortium meeting

https://athleteproject.eu/wp-content/uploads/2024/01/ATH-group-picture-Grenoble.jpg Over 80 project partner participants gathered in Grenoble, France and online to attend the sixth annual ATHLETE consortium meeting, held from 23-24 January. The event, hosted by INSERM, saw ...
Out now: Fifth edition of the European Human Exposome Network newsletter

Out now: Fifth edition of the European Human Exposome Network newsletter

Read about the latest updates, new tools, and upcoming events from the European Human Exposome Network (EHEN). https://athleteproject.eu/wp-content/uploads/2023/11/ATHLETE-Newsletter-visual.png In this fifth edition of the EHEN newsletter, we explore some of ...
From womb to tomb: tackling diseases by knowing the surrounding influences

From womb to tomb: tackling diseases by knowing the surrounding influences

In October 2023, ATHLETE’s project coordinator Martine Vrijheid featured in the European Commission’s Horizon EU Research and Innovation Magazine, in which she explains how and why researchers are examining the ...

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