The Human Exposome

The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.

It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.

The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains one person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.

The Human Exposome

The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.

It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.

The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains onea person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.

The Human Exposome

Latest News

ATHLETE Fellowships: a conversation with Aidan Watmuff

ATHLETE Fellowships: a conversation with Aidan Watmuff

Through ATHLETE’s Fellowship Programme, early-career researchers working on the human exposome are given the opportunity to collaborate with other consortium partners around the world. We talked with Aidan Watmuff, a ...
Green spaces in cities have a positive effect on children’s brain structure, new study finds

Green spaces in cities have a positive effect on children’s brain structure, new study finds

https://athleteproject.eu/wp-content/uploads/2024/04/ATHLETE-greenspaces-positive-effect-on-childrens-brain.png In a new study that could help city planners and policy-makers create healthier urban environments to work and live in, researchers from ATHLETE’s partner organisation ISGlobal found that exposure ...
Highlights from the ATHLETE project's sixth annual consortium meeting

Highlights from the ATHLETE project’s sixth annual consortium meeting

https://athleteproject.eu/wp-content/uploads/2024/01/ATH-group-picture-Grenoble.jpg Over 80 project partner participants gathered in Grenoble, France and online to attend the sixth annual ATHLETE consortium meeting, held from 23-24 January. The event, hosted by INSERM, saw ...

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