The main goal of this WP is to systematically characterise the effects of the in-utero exposome on early-organ development and growth, using data from the new ATHLETE cohorts with novel state-of-the-art data collection on exposures and outcomes in the earliest phase of life (Gen R Next, BiSC, SEPAGES, Piccolipiù, and ENVIRONAGE).
Outcomes are measured with recently developed imaging techniques of the embryo, foetus, neonate and infant, combined with detailed measurements, observations and questionnaires.
We will focus on:
- General growth and placental function
- Brain growth and development
- Cardiovascular structure and development
- Lung and airways growth and development