ATHLETE looks at
the increasing number of new chemical pollutants present in plastic toys, personal care products, pesticides, food packaging and other items we come in contact with on a daily basis, which were not detectable in biosamples collected even 10 years ago.
Chronic diseases have part of their origin in early life,
where there are vulnerable periods of rapid organ development.
ATHLETE studies
the effects of numerous environmental hazards on human health in order to improve the quality of life.
Behavioural and lifestyle factors such as diet, physical activity, sleep and screen time form part of the personal exposome
studied by the ATHLETE project.
The Human Exposome
The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.
It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.
The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains one person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.
The Human Exposome
The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.
It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.
The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains onea person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.
Latest News
Out now: Fifth edition of the European Human Exposome Network newsletter
From womb to tomb: tackling diseases by knowing the surrounding influences
ATHLETE Fellowships: a conversation with Sophie Blaauwendraad
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