The Human Exposome

The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.

It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.

The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains one person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.

The Human Exposome

The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.

It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.

The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains onea person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.

The Human Exposome

Latest News

Here's the second edition of European Human Exposome Network newsletter! Spring 2022

Here’s the second edition of European Human Exposome Network newsletter! Spring 2022

In this second edition of the European Human Exposome Network (EHEN) you can read about the overall progress and an update of the nine projects within the network Download the ...
A New study Provides Valuable Information on DNA Methylation and Gene Expression in Children

A New study Provides Valuable Information on DNA Methylation and Gene Expression in Children

The findings could become a powerful tool to better understand the association between environmental exposures in childhood, epigenetic changes and disease https://athleteproject.eu/wp-content/uploads/2022/04/Alex-Losada-Ajtm-Bcn-zona-pacificada-de-lEscola-Lavinia-300x142.jpg Photo: Alex Losada / Barcelona City Council A new ...
Higher Exposure to Bisphenol A in the Womb Associated with Increased Risk for Asthma and Wheezing in School-Age Girls

Higher Exposure to Bisphenol A in the Womb Associated with Increased Risk for Asthma and Wheezing in School-Age Girls

Study of over 3,000 children from six European countries examines possible effects of prenatal exposure to bisphenols on respiratory health in childhood https://athleteproject.eu/wp-content/uploads/2022/03/Photo-Mariona-Gil-Barcelona-City-Council-300x142.jpg Photo: Mariona Gil / Barcelona City Council ...
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Twitter

Per coloro che nutrono una vera passione per le sfide metodologiche nell’analisi dei driver dell’#esposoma c'è il bando ideale (deadline: 22.06) #ATHLETEProject @unito 👉 http://www.cpo.it/it/bacheca/

2nd day of #EHEN meeting with more project and working group updates, including LT from our project coordinator @SylvainSebert. More importantly is the networking and discussions (here with #ATHLETEproject and #EXPANSE) enabled by attending meetings in person finally! #exposome

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