The Human Exposome

The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.

It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.

The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains one person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.

The Human Exposome

The Human Exposome refers to the totality of environmental exposures over a lifetime from conception to adulthood.

It shifts our approach to studying the environment from the traditional ‘one exposure, one disease’ framework to a more holistic approach that explores multiple environmental factors affecting health.

The exposome is comprised of three overlapping domains: the personal, external and internal exposome. The personal exposome contains onea person’s exposure to chemical pollutants, behavioural and lifestyle factors. The external exposome includes urban, built and transport settings, natural and green spaces, social aspects and climate. The internal exposome implies the biological responses to the personal and external exposome, including metabolism, epigenetics, aging, gut microbiota and stress.

The Human Exposome

Latest News

How does early-life exposure to environmental pollutants affect our health? New flyer and video from the ATHLETE project.

How does early-life exposure to environmental pollutants affect our health? New flyer and video from the ATHLETE project.

The flyer and the video illustrate how ATHLETE can help us better understand how environmental pollutants affect our health over a lifetime and how we can prevent this from happening ...
EU Green Week 2021 – Zero Pollution and the European Green Deal

EU Green Week 2021 – Zero Pollution and the European Green Deal

Understanding the Human Exposome’s effect on our health can aid the EU in reaching its Zero Pollution ambition. Pollution harms our health and knows no borders. It affects everybody – ...
Register and join the EHEN online conference - 11th June - 10h-17h (CET)

Register and join the EHEN online conference – 11th June – 10h-17h (CET)

Decoding the exposome: the biggest influencer on health! You can now register for this online event. Please do so before June 10th, 17h CET. Poster Session During lunch, we will organise ...
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